Many types of plants, trees, and shrubs should be pruned in the spring. However, some plants must be pruned before there is new growth, so that means by early spring or even in the winter. Crape Myrtles should always be pruned in late winter/early spring to avoid damage to their growth habit. Done properly, with sharp blades and clean cuts, your vegetation will look great for the spring and summer by correct horticultural pruning practices.